Tea and Coffee Can Result DNA Damage Like Cancer Drugs

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Tea and Coffee Can Result DNA Damage Like Cancer Drugs

 

Jakarta, Some natural ingredients are claimed to be safer for the body than some chemicals. For materials like coffee and tea, there seems to be an exception. One study found that the ingredients in the drink can cause DNA damage such as chemotherapy drugs. Some scientists from the Johns Hopkins Kimmel Cancer Center tested the impact of some foods and food flavors in the laboratory. Finally found that the cancer-protecting gene in question p53 will also be activated by compounds in black tea, green tea, coffee and some spices used to raise the smoky taste in meat. In a report published in the journal Food and Chemical Toxicology, researchers found that drinks and foods can increase the p53 to 30 times as much activity when added to cells. This impact is commensurate with the effects of chemotherapy drugs called etoposide in squeezing cancer-causing genes. "" We found that liquid smoke when diluted a thousand fold is still as strong as etoposide concentrations in cancer patients being treated with etoposide. In fact, it works the same way. Etoposide causes DNA damage to patients, that's how you get rid of cancer, but it also has its risks, "said the researcher, Dr Scott Kern. The p53 gene is stimulated when DNA is damaged and causes a series of responses that attempt to repair DNA. The greater the damage to DNA, so the more p53 content. Some scientists have made the decision that the high content of p53 is a sign that there is pressure on DNA. In laboratory experiments, the cells that were given black tea, green tea, coffee and liquid seasonings showed the hustle of p53 trying hard to repair damaged DNA. The test results with different tastes such as fish flavorings, oyster sauce, peppers, wasabi powder and kim chee does not show the same p53 busyness. Researchers believe that the inequality is found in some chemicals such as pyrogalol acid and gallic acid which can lead to DNA damage and activate p53. Pirogalol is found in smoked foods, hair dye, tea, cigarette smoke and coffee. Moderate acid is the type of pirogalol most widely found in coffee and tea. In spite of that, Kern warned that his research does not recommend people to stop consuming tea, coffee or flavorings, but called for the importance of further research. Some of the damage caused by the chemical may also still be fixed by the p53 gene. (pah / vta)